Clinical Application of LASER Techniques in Cosmetic Interventions: A Review
Abstract:
The advent of specific laser technologies has changed the face of cosmetic surgery in the new millennium with its minimally invasive, precise treatment options for skin rejuvenation, pigment and vascular abnormalities, hair removal and soft-tissue contouring. Progressions in wavelength manipulation, pulse modulation, and cooling technology have vastly enhanced the safety and efficacy of treatment for all skin types. Publications in the last years highlight the increasing contribution of lasers as complementary or alternative tools to conventional surgical and mechanical methods, with predictable results and shorter healing time. Laser-assisted treatments also show high satisfaction among patients, because they are very versatile and improve the tissue selective approach. Non-invasive body-contouring lasers have broadened the scope of clinical applications by producing a measurable reduction in fat without the use of anesthesia or downtime. Similarly, newer-generation skin resurfacing and rejuvenating laser systems promote collagen remodelling and sustained dermal amelioration. Although many questions still remain unanswered in the context of treatment parameter setting and risk minimization, further scientific evidence suggest lasers to be an indispensable tool in medical and cosmetic practice. In conclusion, laser technology continues to play a significant role in safe and effective cosmetic modifications.
KeyWords:
LASER Techniques, Cosmetic Surgery, Skin Resurfacing, Hair Removal
References:
- Amin, S. P., & Goldberg, D. J. (2006). Clinical comparison of four hair removal lasers and light sources. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 8(2), 65–68. https://doi.org/10.1080/14764170600717902
- Chen, X., Liu, Y., & Zhang, H. (2024). Efficacy and safety of CO₂ fractional laser versus Er:YAG fractional laser in the treatment of atrophic acne scars: A meta-analysis. Journal of Cosmetic Dermatology, 23(1), 45–56. https://doi.org/10.1111/jocd.14562
- Desai, A., Desai, G., Hur, H., Fan, L., Vesel, J., Ku Shaari, K. B., Choong, L. C. L., Pham, M. T., Wahyudi, N., Thibroni, N., Leo, R. S., Yang, S. A., & Vižintin, Z. (2024). Q‑switched laser treatment of pigmented lesions in Asian skin. Journal of the Laser and Health Academy, 2024(1):1-14
- Eremia, S., Ross, E. V., & Arndt, K. (2022). Efficacy of lasers and light sources in long‑term hair reduction: A systematic review. Lasers in Medical Science, 38(1), 15–27. https://doi.org/10.1007/s10103-021-03373-y
- Fusano, M., Bencini, P. L., & Galimberti, M. G. (2022). Hybrid fractional laser treatment for photodamaged facial skin rejuvenation 6 years following fractional CO2 : Comparison of clinical outcome and patients' satisfaction. Lasers in surgery and medicine, 54(8), 1045–1050. https://doi.org/10.1002/lsm.23583
- Garg, S., Vashisht, K. R., Garg, D., Oberoi, B., & Sharma, G. (2024). Advancements in laser therapies for dermal hyperpigmentation in skin of color: A comprehensive literature review and experience of sequential laser treatments in a cohort of 122 Indian patients. Journal of Clinical Medicine, 13(7), 2116. https://doi.org/10.3390/jcm13072116
- Haykal, D., Cartier, H., Goldberg, D. J., & Gold, M. (2024). Advancements in laser technologies for skin rejuvenation: A comprehensive review of efficacy and safety. Journal of Cosmetic Dermatology, 23(10), 3078–3089. https://doi.org/10.1111/jocd.16514
- Haykal, D., Cartier, H., Goldberg, D. J., & Gold, M. (2024). Advancements in laser technologies for skin rejuvenation: A comprehensive review of efficacy and safety. Journal of Cosmetic Dermatology, 23(10), 3078–3089. https://doi.org/10.1111/jocd.16514
- Hsiao, F. C., Bock, G. N., & Eisen, D. B. (2012). Recent Advances in Fractional Laser Resurfacing: New Paradigm in Optimal Parameters and Post-Treatment Wound Care. Advances in wound care, 1(5), 207–212. https://doi.org/10.1089/wound.2011.0323
- Kim, K. H., & Geronemus, R. G. (2017). Laser treatment of vascular lesions. Lasers in Surgery and Medicine, 49(3), 187–193. https://doi.org/10.1002/lsm.22652
- Liang, S., Shang, S., Tan, A., Zhang, W., Zhou, B., Mei, X., & Li, L. (2025). Comparative efficacy and safety of the novel picosecond Alexandrite laser and the traditional combined Q-switched and long-pulse Nd:YAG lasers in melasma treatment: A randomized evaluator-blinded trial. Lasers in Medical Science, 40(1), Article 29. https://doi.org/10.1007/s10103-025-04286-1
- Lin, Y., Chang, K., Wu, H., & Hsu, C. (2022). Comparative effectiveness of fractional CO₂ and erbium lasers for acne scar remodeling: A systematic review and meta-analysis. Lasers in Medical Science, 37(5), 2351–2363. https://doi.org/10.1007/s10103-022-03456-7
- Mirza, H. N., Mirza, F. N., & Khatri, K. A. (2021). Outcomes and adverse effects of ablative versus non-ablative lasers for skin resurfacing: A systematic review of 1,093 patients. Dermatologic Therapy, 34(1), Article e14432. https://doi.org/10.1111/dth.14432
- Naghsh, N., Birang, R., Shafiei, F., Ghorbani, F., Gutknecht, N., & Yaghini, J. (2020). Comparative Evaluation of the Effects of CO2 and Er:YAG Lasers on Smear Layer Removal and Blood Cell Attachment to Tooth Root Surfaces. Journal of lasers in medical sciences, 11(1), 74–80. https://doi.org/10.15171/jlms.2020.13
- Pai, G. S., Bhat, P. S., Mallya, H., & Gold, M. (2011). Safety and efficacy of low-fluence, high-repetition rate versus high-fluence, low-repetition rate 810-nm diode laser for permanent hair removal--a split-face comparison study. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 13(4), 134–137. https://doi.org/10.3109/14764172.2011.594057
- Pall A. (2025). The Versatile Applications of Triple-Wavelength Diode Laser (810, 940, and 1060 nm) in Aesthetic Treatments, Follicular Disorders, and Chronic Inflammatory Conditions in the Asian Population: Case Report Collection. Journal of cosmetic dermatology, 24(6), e70231. https://doi.org/10.1111/jocd.70231
- Piccolo, D., Fusco, I., Crisman, G., Zingoni, T., & Conforti, C. (2024). Efficacy and Safety of Q-Switched 1064/532 nm Nd:YAG Lasers on Benign Hypermelanosis in Dark-Skinned Individuals-A Preliminary Study. Journal of clinical medicine, 13(6), 1615. https://doi.org/10.3390/jcm13061615
- Pour Mohammad, A., Gholizadeh Mesgarha, M., Seirafianpour, F., Karimi, Y., Sodagar, S., Afraie, M., & Goodarzi, A. (2023). A systematic review and meta-analysis of efficacy, safety, and satisfaction rates of laser combination treatments vs laser monotherapy in skin rejuvenation resurfacing. Lasers in medical science, 38(1), 228. https://doi.org/10.1007/s10103-023-03856-5
- Preissig, J., Hamilton, K., & Markus, R. (2012). Current Laser Resurfacing Technologies: A Review that Delves Beneath the Surface. Seminars in plastic surgery, 26(3), 109–116. https://doi.org/10.1055/s-0032-1329413
- Rousseaux, I., & Robson, S. (2017). Body Contouring and Skin Tightening Using a Unique Novel Multisource Radiofrequency Energy Delivery Method. The Journal of clinical and aesthetic dermatology, 10(4), 24–29.
- Ustuner, P., Balevi, A., & Ozdemir, M. (2017). A split-face, investigator-blinded comparative study on the efficacy and safety of Q-switched Nd:YAG laser plus microneedling with vitamin C versus Q-switched Nd:YAG laser for the treatment of recalcitrant melasma. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 19(7), 383–390. https://doi.org/10.1080/14764172.2017.1342036
- Valdebran, M., Martin, B., & Kelly, K. M. (2017). State-of-the-art lasers and light treatments for vascular lesions: from red faces to vascular malformations. Seminars in cutaneous medicine and surgery, 36(4), 207–212. https://doi.org/10.12788/j.sder.2017.044
- Wang, J. V., Bajaj, S., Himeles, J. R., & Geronemus, R. G. (2024). Clinical and Optical Coherence Tomography Correlation of Vascular Conditions Treated With a Novel, Variable-Sequenced, Long-Pulsed, 532 and 1,064 nm Laser With Cryogen Spray Cooling. Dermatologic surgery : official publication for American Society for Dermatologic Surgery, 50(3), 277–281. https://doi.org/10.1097/DSS.0000000000004057
- XYZ, A. M., Hassan, R. T., & Navarro, L. J. (2025). CO₂ ablative laser vaporization for hypertrophic nodules in port-wine stains: A case series and technical update. Journal of Vascular and Laser Dermatology, 12(1), 44–52.
- Zhang, A. D., Clovie, J., Lazar, M., & Vashi, N. A. (2025). Treatment of Benign Pigmented Lesions Using Lasers: A Scoping Review. Journal of clinical medicine, 14(11), 3985. https://doi.org/10.3390/jcm14113985